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An Evaluation of Neuronal PARP‐1 and Caspase‐3 Levels in the Brain Tissue of Female Rats Exposed to Electromagnetic Fields at Different Gestational Stages   
Yazarlar (4)
Kıymet Kübra Tüfekci
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Musa TATAR Doç. Dr. Musa TATAR
Kastamonu Üniversitesi, Türkiye
Abdalla Ahmed Eldaw Elamin
RAK Medical and Health Sciences University, Birleşik Arap Emirlikleri
Süleyman Kaplan
Ondokuz Mayıs Üniversitesi, Türkiye
Devamını Göster
Özet
Foetal exposure to electromagnetic fields (EMFs) may cause marked neurocognitive impairment, although the mechanisms involved are still unclear. EMF induces region‐specific neuronal and astroglial death in the rat hippocampus. Poly (ADP‐ribose) polymerase‐1 (PARP‐1) regulates necrosis, apoptosis and other cellular processes occurring following injury. This study, therefore, investigated whether PARP‐1 also regulates neuronal responses in the hippocampus of rats subjected to EMF radiation during different developmental periods. Male and female rats were first allowed to mate in separate cages. Rats identified as pregnant were then divided into four groups. A 900‐MHz EMF was applied for 2 h daily on gestational days (GD) 1--7, GD 8--14 and GD 15--21. The female offspring were sacrificed at the end of the 28th postnatal day, and PARP‐1 and Caspase‐3 expressions in the hippocampus were then ...
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Açık Erişim International Journal of Developmental Neuroscience
Dergi ISSN 1873-474X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCOPUS, SCI-Exp
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 02-2025
Cilt No 85
Sayı 1
Doi Numarası 10.1002/jdn.70010
Makale Linki https://doi.org/10.1002/jdn.70010