img
img
Effect of 900 MHz Electromagnetic Field Exposure During Different Trimesters of Pregnancy on TRPM2‐Mediated Ferroptosis and Neurotoxicity in the Trigeminal Ganglion of Rats: Protective Role of Ferrostatin‐1     
Yazarlar (4)
Dr. Öğr. Üyesi Yener YAZĞAN Dr. Öğr. Üyesi Yener YAZĞAN
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Kıymet Kübra TÜFEKCİ Doç. Dr. Kıymet Kübra TÜFEKCİ
Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Betül YAZĞAN Dr. Öğr. Üyesi Betül YAZĞAN
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Musa TATAR Doç. Dr. Musa TATAR
Kastamonu Üniversitesi, Türkiye
Devamını Göster
Özet
Electromagnetic field (EMF) exposure, unavoidable in modern life, is linked to oxidative stress and ferroptosis, processes linked to neurodevelopmental disorders. This study investigated the effects of EMF exposure during different pregnancy trimesters on rat offspring trigeminal ganglia (TGs), focusing on transient receptor potential melastatin 2 (TRPM2) ion channels, and assessed the neuroprotective potential of ferrostatin‐1 (Fer), a ferroptosis inhibitor, against EMF‐induced damage. Pregnant rats were exposed to 900 MHz EMF for 2 h/day during early (1--7 days, EMF 1), mid (8--14 days, EMF 2), or late (15--21 days, EMF 3) gestation. Fer (2.5 µmol/kg, i.p.) was administered immediately after daily EMF exposure in Fer treatment groups. Offspring TG tissues were analyzed on postnatal Day 28 using histopathological, immunohistochemical, and biochemical approaches. EMF exposure significantly reduced ...
Anahtar Kelimeler
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Developmental Neurobiology
Dergi ISSN 1932-8451 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili Türkçe
Basım Tarihi 10-2025
Cilt No 85
Doi Numarası 10.1002/dneu.23013
Makale Linki https://doi.org/10.1002/dneu.23013