| Yazarlar (4) |
Ferdane Danisman Kalindemirtas
Erzincan Üniversitesi, Türkiye |
|
Ishak Afsin Kariper
Erciyes Üniversitesi, Türkiye |
Doç. Dr. Dilşad ÖZERKAN
Kastamonu Üniversitesi, Türkiye |
|
Durdane Serap Kuruca
istanbul Atlas Üniversitesi, Türkiye |
| Özet |
| Objective: The term" triple-negative breast cancer"(TNBC) is used to describe tumours that do not express oestrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER2). TNBC tends to be more aggressive than other types of breast cancer. Current antineoplastic drugs have limited treatment options for malignant breast cancer owing to their narrow therapeutic index, toxicity, resistance, and non-selectivity. Therefore, there is a need for the prompt development of new medicinal drugs for TNBC. Here, we investigated the growth inhibition potential of carmofur-bonded silver nanoparticles (AgNPs-Car) on two TNBC cell lines, MDA-MB-231 and 4T1, and compared the effects with non-cancerous Human umbilical vein endothelial cells (HUVECs).Material and Methods: AgNPs-Car were synthesised and characterised by FTIR, DLS, SEM, and EDX. The anticancer effect was ... |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale |
| Dergi Adı | Journal of Istanbul Faculty of Medicine |
| Dergi Tarandığı Indeksler | ESCI, TR DİZİN |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2025 |
| Cilt No | 88 |
| Sayı | 2 |
| Sayfalar | 118 / 128 |
