Association of c-reactive protein albumin ratio with disease severity and nutritional risk in patients with acute ischemic stroke
Yazarlar (4)
Dr. Öğr. Üyesi Tuğba TATAR Kastamonu Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fatmanur Hümeyra ZENGİN Kastamonu Üniversitesi, Türkiye
Rümeysa Yüksel
Bağımsız Araştırmacılar
Bağımsız Araştırmacılar
Eda Nur Afacan
Bağımsız Araştırmacılar
Bağımsız Araştırmacılar
| Makale Türü |
Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | Clinical Science of Nutrition | ||
| Dergi ISSN | 2667-6222 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2025 |
| Cilt / Sayı / Sayfa | 7 / 3 / 158–168 | DOI | 10.62210/ClinSciNutr.2025.120 |
| Makale Linki | https://clinscinutr.org/article/view/120/140 | ||
| UAK Araştırma Alanları |
Beslenme ve Diyetetik
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| Özet |
| Background CAR is a novel biomarker that predicts disease prognosis in inflammation-related diseases such as stroke. Aim We aimed to evaluate the relationship between CAR and disease severity and nutritional status in patients with acute ischemic stroke (AIS). Method This research is a cross-sectional, descriptive study. The sample consists of 99 AIS patients. A face-to-face interview questionnaire was used to determine the sociodemographic characteristics. The nutritional status was assessed by NRS-2002, SNAQ, MUST, and SGA, and disease status was determined by NIHSS and Modified Rankin Scale. Anthropometric measurements were taken. Biochemical parameters were obtained retrospectively from the patient records. Results 21.2% (n = 21) of the patients had an NRS-2002 score ≥ 3. When the combined effect of NIHSS and MUST on CAR was evaluated using Univariate ANOVA, the main effect of both MUST and NIHSS separately was significant. However, the combined effect of NIHSS and MUST was not found (p > 0.05). CAR of those at low risk of malnutrition (6.2±13.7) was significantly lower than that of those at moderate risk of malnutrition (13.7±17.2) according to MUST (p < 0.05). NRS-2002 significantly predicted a higher CAR (B = 10.89, p = 0.002). CAR significantly predicted higher NIHSS (B = 0.02, p = 0.003). The total effect analysis showed that malnutrition was positively associated with disease severity (B = 0.72, p = 0.002). Discussion This study revealed that nutritional risk (NRS-2002) was significantly associated with disease severity (NIHSS), both directly and indirectly. CAR mediated this relationship. Using CAR … |
| Anahtar Kelimeler |
| nutrition | CAR | NRS-2002 | NIHSS | MUST |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |