Supported silver nanoparticles over Metronidazole modified-single walled carbon nanotubes for overcoming anti-microbial properties, anti-cancer effect, and apoptosis induction on human gastric cancer cell line
Yazarlar (5)
Shirin Mahmoudi Islamic Azad University, Central Tehran Branch, İran
Maryam Otadi Islamic Azad University, Central Tehran Branch, İran
Malak Hekmati Islamic Azad University, Tehran Medical Branch, İran
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, Central Tehran Branch, İran
Azadeh Sadat Shekarabi
Islamic Azad University, Central Tehran Branch, İran
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Results in Chemistry
Dergi ISSN 2211-7156 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 01-2024
Cilt / Sayı / Sayfa 7 / 1 / – DOI 10.1016/j.rechem.2024.101519
Makale Linki https://doi.org/10.1016/j.rechem.2024.101519
Özet
One of the most important goals of current research in the medical field is to identify treatments for antimicrobial resistance (AMR) and cancer. The latest developments in nanotechnology have provided opportunities to develop novel nanomaterials that can overcome the limitations of current treatments. In this regard, carbon nanotubes (CNTs) are considered potential nano-tools with attractive implications. The analysis of MTZ/SWCNT/AgNPs in this study was done using different techniques, including SEM, TEM, FTIR, XRD, and EDX. Antibacterial activity was assessed for MTN/SWCNT/AgNPs against Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus. The effects of MTZ/SWCNTs/AgNPs on mitochondrial and apoptotic activities in human gastric cancer (AGS) were evaluated. Overall, new CNTs were produced efficiently. MTZ/SWCNTs/AgNPs are considered efficient antibacterial and anticancer agents for biological applications.
Anahtar Kelimeler
Antibacterial | Anticancer | Carbon Nanotubes | Metronidazole | Silver Nanoparticle