Cholesterol Interactions with Fatty Acids and DMPC Phospholipids of Liver Membranes
Yazarlar (2)
Arina Rahimi Islamic Azad University, Science And Research Branch, İran
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, Science And Research Branch, İran
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Oriental Journal of Chemistry | ||
| Dergi ISSN | 0970-020X Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2016 |
| Cilt / Sayı / Sayfa | 32 / 6 / 2957–2965 | DOI | 10.13005/ojc/320615 |
| Makale Linki | http://www.scopus.com/inward/record.url?eid=2-s2.0-85008158212&partnerID=MN8TOARS | ||
| Özet |
| Cholesterol and fatty acids is important subject in liver to different model of regulation for realizing the evolution of vertebrates. The major solubility of cholesterol in bilayers of glycerolphospholipids is between 65 and 50 mole%, relevant on the bilayer of lipid membrane but they cannot alone form multi layered structures. Livers from the transgenic rat showed increases in mRNAs encoding various enzymes of cholesterol synthesis, the LDL's receptor and fatty acid synthesis. Based on our previous works we have modeled and simulated various molecules of that Cholesterol in binding to membrane. A number of computational chemistry studies carried out to understand of the cholesterol parallel to fatty acid synthesis (FAS) for preventing the fatty liver disease. In this work ELF, LOL, ECP, electrical properties such as electron densities, energy densities, and potential energy densities, eta index for some of the fatty acids have been calculated. |
| Anahtar Kelimeler |
| Cholesterol | Drug design | Fatty acid | Liver | Nano-biotechnology |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 2 |