Thermodynamic study of interaction of TSPP, CoTsPc, and FeTsPc with calf thymus DNA
 
Yazarlar (3)
Prof. Dr. Majıd MONAJJEMI Islamic Azad University, İran
H. Aghaie
Islamic Azad University, İran
F. Naderi
Islamic Azad University, İran
Makale Türü Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Biochemistry Moscow
Dergi ISSN 0006-2979 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 06-2007
Cilt / Sayı / Sayfa 72 / 6 / 652–657 DOI 10.1134/S0006297907060089
Makale Linki http://www.scopus.com/inward/record.url?eid=2-s2.0-34547243082&partnerID=MN8TOARS
Özet
The interaction of two water soluble phthalocyanines, cobalt(II) 4,4′,4″,4′″-tetrasulfo-phthalocyanine (CoTsPc) and iron(II) 4,4′,4″,4′″-tetrasulfo-phthalocyanine (FeTsPc), and one water soluble porphyrin, tetra sodium mesotetrakis(p-sulfophenyl) porphyrin (TSPP), with calf thymus DNA has been studied by UV-Vis spectroscopy at five different temperatures (20, 25, 30, 35, and 40°C). The optical absorption spectra of these materials were analyzed to obtain binding constants and stoichiometries using SQUAD software. The results show that the best fitting corresponds to a 1: 1 complex model between a base pair of DNA and these materials. All of the studied porphyrin and phthalocyanines showed strong electrolyte effect, and increasing NaCl concentration induced self-aggregation of these materials. © Nauka/Interperiodica 2007.
Anahtar Kelimeler
DNA | Phthalocyanine | Porphyrin | SQUAD
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 43
Scopus 78
Thermodynamic study of interaction of TSPP, CoTsPc, and FeTsPc with calf thymus DNA

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