Characterization and Functionalization of Diabetes Medication (BNEJa): A Step Forward in Nano Drug Delivery System
Yazarlar (2)
Dr. Öğr. Üyesi Fatemeh MOLLAAMIN Kastamonu Üniversitesi, Türkiye
Prof. Dr. Majıd MONAJJEMI Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Biointerface Research in Applied Chemistry | ||
| Dergi ISSN | 2069-5837 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCOPUS | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2026 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 15-02-2026 |
| Cilt / Sayı / Sayfa | 16 / 1 / 8–0 | DOI | 10.33263/BRIAC161.008 |
| Makale Linki | https://doi.org/10.33263/BRIAC161.008 | ||
| UAK Araştırma Alanları |
Fen Bilimleri ve Matematik
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| Özet |
| In this research, the interaction between the anti-diabetic drug of (BNEJa) and armchair single-walled carbon nanotube (SWCNT) has been calculated with density functional theory (DFT) to ameliorate carbon nanotube drug carriers as the applied sensors in drug delivery systems. BNEJa shows NMR shielding between 10–600 ppm, with a sharp peak at 25 ppm and several weak peaks between 100–450 ppm. The hydrogens involved in the O–H of PO3 groups have remarked the high degeneracy in NMR chemical shielding tensors. The largest fluctuation in atomic charge has been observed for the oxygen atoms in the O–H of PO3 groups, as the electronegative atoms in the formation of potent chelation with the carbon nanotube using the drug delivery method, suggesting the modeling of (BNEJa)@ SWCNT. Moreover, the electric potential (Ep) as the amount of work energy through transferring the electric charge from one site to another site in the presence of an electric field has been measured for blood pressure (BP) agent of (BNEJa)@ SWCNT complex using CAM–B3LYP/EPR–III, 6–311+ G (d, p) level of theory. So, the electric potential of the NQR method for elements of N, P, O, and F, dealing with the interaction site between the BP agent of (BNEJa) and the surface of SWCNT in aqueous medium. The parameter values have shown good stability of the BP agent during Langmuir adsorption on the SWCNT sensor. |
| Anahtar Kelimeler |
| computational method | diabetes medication | drug delivery | SWCNT sensor |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |