| Yazarlar |
Kerem Canlı
Dokuz Eylül Üniversitesi, Türkiye |
|
Dilay Turu
|
|
Atakan Benek
|
|
Mustafa Eray Bozyel
|
|
Özcan Şimşek
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
Prof. Dr. Ergin Murat ALTUNER
Türkiye |
| Özet |
| In this study, the chemical composition and biological activity of Allium scorodoprasum subsp. jajlae (Vved.) Stearn were investigated for the first time, focusing on its antimicrobial, antioxidant, and antibiofilm properties. A GC-MS analysis was employed to evaluate the composition of its secondary metabolites, identifying linoleic acid, palmitic acid, and octadecanoic acid 2,3-dihydroxypropyl ester as the major compounds in ethanol extract. The antimicrobial activity of A. scorodoprasum subsp. jajlae was assessed against 26 strains, including standard, food isolate, clinical isolate, and multidrug-resistant ones, as well as three Candida species using the disc diffusion method and the determination of the minimum inhibitory concentration (MIC). The extract showed strong antimicrobial activity against Staphylococcus aureus strains, including methicillin-resistant and multidrug-resistant strains, as well as Candida tropicalis and Candida glabrata. Its antioxidant capacity was evaluated using the DPPH method, revealing a high level of antioxidant activity in the plant. Additionally, the antibiofilm activity of A. scorodoprasum subsp. jajlae was determined, demonstrating a reduction in biofilm formation for the Escherichia coli ATCC 25922 strain and an increase in biofilm formation for the other tested strains. The findings suggest potential applications of A. scorodoprasum subsp. jajlae in the development of novel antimicrobial, antioxidant, and antibiofilm agents. |
| Anahtar Kelimeler |
| Allium scorodoprasum subsp. jajlae | antibiofilm activity | antimicrobial activity | antioxidant activity | GC-MS analysis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | CURRENT ISSUES IN MOLECULAR BIOLOGY |
| Dergi ISSN | 1467-3037 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 06-2023 |
| Cilt No | 45 |
| Sayı | 6 |
| Sayfalar | 4970 / 4984 |
| Doi Numarası | 10.3390/cimb45060316 |
| Makale Linki | https://www.mdpi.com/1467-3045/45/6/316 |
| Atıf Sayıları | |
| WoS | 1 |
| SCOPUS | 1 |
| Google Scholar | 2 |
