Biochemical Composition, and In Vitro Antimicrobial and Antioxidant Activities of Salvia fruticosa, An Ethnomedicinal Plant
Yazarlar (6)
M. E. Bozyel
Dokuz Eylül Üniversitesi, Türkiye
K. Canli
Dokuz Eylül Üniversitesi, Türkiye
A. Benek
Kastamonu University, Türkiye
O. Simsek
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
I. Akata
Ankara Üniversitesi, Türkiye
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Applied Ecology and Environmental Research (Q4)
Dergi ISSN 1589-1623 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2023
Kabul Tarihi Yayınlanma Tarihi 01-01-2023
Cilt / Sayı / Sayfa 21 / 4 / 3243–3256 DOI 10.15666/aeer/2104_32433256
Makale Linki https://www.aloki.hu/pdf/2104_32433256.pdf
UAK Araştırma Alanları
Biyokimya
Özet
Salvia fruticosa (Anatolian sage) is a medicinal plant with a natural distribution in the Central and Eastern Mediterranean. It has ethnomedicinal uses in traditional medicine. The aim of this study was to investigate the biochemical composition and in vitro antimicrobial and antioxidant activities of S. fruticosa. The in vitro antimicrobial activity of S. fruticosa ethanol extract (SFEt) by disk diffusion method against thirty-nine bacterial (including eleven multidrug-resistant strains) and two fungal strains was examined. The determination of antioxidant activity was carried out by the DPPH method. The identification of biochemical composition was by GC-MS. Twenty-three components were identified in SFEt and the main one was D-camphor (20.27%). SFEt has antimicrobial activity against a wide range of microorganisms tested. The highest activity has been demonstrated against Staphylococcus epidermidis DSMZ 20044 (ST12) as a Gram-positive bacteria with a 21 mm zone of inhibition and Proteus vulgaris (MDR6) as a Gram-negative bacteria with a 13 mm zone of inhibition. Also, the data from Streptococcus pneumonia (MDR7) was very striking because a higher activity has been observed than fourteen positive controls. SFEt showed antioxidant activity almost as high as Ascorbic acid. These results have shown that S. fruticosa has a high antimicrobial and antioxidant potential.
Anahtar Kelimeler
Anatolian sage | disk diffusion | DPPH | GC-MS | multidrug-resistant bacteria | Salvia fruticosa
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 3
Scopus 4
Google Scholar 5
Biochemical Composition, and In Vitro Antimicrobial and Antioxidant Activities of Salvia fruticosa, An Ethnomedicinal Plant

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