Antimicrobial Activity and Chemical Composition Screening of Epilobium montanum Root
Yazarlar (4)
Prof. Dr. Kerem Canlı Dokuz Eylül Üniversitesi, Türkiye
Ali Yetgin
Izmir Yüksek Teknoloji Enstitüsü, Türkiye
Prof. Dr. Ilgaz Akata Ankara Üniversitesi, Türkiye
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Indian Journal of Pharmaceutical Education and Research
Dergi ISSN 0019-5464 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2017
Kabul Tarihi Yayınlanma Tarihi 25-07-2017
Cilt / Sayı / Sayfa 51 / 3 / – DOI 10.5530/ijper.51.3s.21
Makale Linki http://www.ijper.org/article/656
UAK Araştırma Alanları
Biyokimya
Özet
Medical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research is required. Epilobium montanum related antimicrobial research doesn't exist, therefore root of this medicinal plant investigation was applied against 17 bacteria and 1 fungi by using disk diffusion method. These microbial species include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy. The results were presented that E. montanum has antimicrobial activity against all tested microbial species except E. coli. Seventeen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed by NMR spectra for 3D structure determination and identification.
Anahtar Kelimeler
Antimicrobial activity | Chemical composition | Disk diffusion method | Epilobium montanum | GC-MS | Medicinal plant