The FTIR analysis of Fomes fomentarius acetone extract-antibiotic interactions in some MDR E. coli strains having active efflux pumps
Yazarlar (3)
Eda Altınöz
Prof. Dr. Ilgaz Akata Ankara Üniversitesi, Türkiye
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
| Bildiri Türü | Tebliğ/Bildiri | Bildiri Dili | İngilizce |
| Bildiri Alt Türü | Özet Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum) | ||
| Bildiri Niteliği | Alanında Hakemli Uluslararası Kongre/Sempozyum | ||
| Kongre Adı | Beyond Sciences Initiative 2023, 8TH Annual International Remote Conference Science&Society | ||
| Kongre Tarihi | 25-02-2023 / 26-02-2023 | ||
| Basıldığı Ülke | Basıldığı Şehir | ||
| Bildiri Linki | https://www.beyondsciences.org/presentation2023/20230403/ | ||
| UAK Araştırma Alanları |
Biyokimya
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| Özet |
| Background Multiple antibiotic resistance continues to be a problem of our time. For this reason, studies of multi-drug resistance continue increasingly, either by the discovery of new antibiotics or understanding the resistance mechanisms and propose solutions to prevent resistance. Bacteria have strong resistance mechanisms and efflux pumps are just one of them. Antibiotic or any substance is pumped from inside the cell to the outside of the cell by efflux pumps. Therefore, there is little or no concentration of the substance left inside the cell. To prevent this, inhibitors have been developed, but their clinical use is not yet suitable due to toxicity problems. Inhibitors derived from natural origins that do not pose a toxicity problem are under investigation. In this study, efflux pump inhibitor potential of macrofungi was studied in vitro and positive results were obtained. Methods In this study, acetone extract of Fomes … |
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