Effect of post-mating TAK-683 (Kisspeptin analog) treatment on luteal morphology and function in suckling goats with lactational anestrus
Yazarlar (1)
Doç. Dr. Gökhan UYANIK Kastamonu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Animal Reproduction Science (Q1) | ||
| Makale Dili | – | Basım Tarihi | 12-2025 |
| Cilt / Sayı / Sayfa | 0 / 0 / 108052–0 | DOI | – |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S037843202500291X | ||
| UAK Araştırma Alanları |
Fen Bilgisi Eğitimi
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| Özet |
| This study aimed to evaluate the effects of TAK-683 administered to suckling goats in lactational anestrus on the 4th day (D4) after mating on luteal function, serum progesterone (P₄) levels, and reproductive performance.Forty-five Aleppo goats were treated with intravaginal sponges containing medroxyprogesterone acetate for 7 days and were injected intramuscularly with 500 IU eCG and 75 µg d-cloprostenol on the day of sponge removal. Thirty-seven goats showed estrus and were mated with fertile bucks (D0). The mated goats were randomly divided into groups to receive subcutaneous administration of saline (Control, n=12), 5 μg TAK-683 (TAK-5, n=12) or 25 μg TAK-683 (TAK-25, n=13) on D4. Transrectal ovarian ultrasonography and blood sampling were performed on D4, D7, D14, D17, and D21, and pregnancy was diagnosed on D35.Regardless of dose, TAK-683 treatment induced the formation of … |
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