Upregulation of miR-125b and miR-23b in plasma might be related with the early pregnancy in Awassi Ewes
Yazarlar (1)
Doç. Dr. Gökhan UYANIK Kastamonu Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Small Ruminant Research | ||
| Makale Dili | – | Basım Tarihi | 07-2025 |
| Cilt / Sayı / Sayfa | 0 / 0 / 107579–0 | DOI | – |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S092144882500152X | ||
| Özet |
| This study investigates the expression patterns of microRNA (miR)-125b and miR-23b during early pregnancy in Awassi ewes. Animal material included 33 ewes consisting of pregnant (PP) (n=14), non-pregnant (PN) (n=14), and control group (n=5) where estrus synchronization was performed but mating was not allowed. Plasma samples were collected on days 7 and 14 post-mating in PP, PN, and control groups. The expression levels of miRNAs were analyzed using qPCR, and progesterone (P4) levels were measured via electrochemiluminescence immunoassay. On day 7, the miR-23b expressions were similar in PN, PP, and control. However, compared to control, miR-23b was found to be upregulated approximately 2-fold in the PP on day 14 compared to PN and control. miR-23b expressions were similar on day 7 and day 14 in PP. miR-125b expression was similar in PN, PP, and control on day 7. Compared … |
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