CURRENT ANESTRUS MANAGEMENT IN EWES: THE RISING ROLE OF NON-STEROIDAL REPRODUCTIVE AGENTS
Yazarlar (1)
Doç. Dr. Gökhan UYANIK Kastamonu Üniversitesi, Türkiye
Makale Türü Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale)
Dergi Adı
Makale Dili Basım Tarihi 12-2025
Makale Linki https://avesis.mku.edu.tr/yayin/17df2dd7-3bfb-43bb-8ba0-998386ce66b4/current-anestrus-management-in-ewes-the-rising-role-of-non-steroidal-reproductive-agents
UAK Araştırma Alanları
Fen Bilgisi Eğitimi
Özet
Seasonal anestrus in ewes results from photoperiod-mediated suppression of hypothalamic GnRH pulsatility, leading to reduced LH secretion and cessation of ovulatory activity. To maintain flock fertility and sustain lamb production during this period, estrus synchronization remains essential, and progestagen-based protocols are widely employed for this purpose. However, despite their practical effectiveness, these steroidal treatments present notable drawbacks, including residue concerns, welfare issues, and environmental impact, highlighting the need for alternative non-steroidal approaches. Recent advances in reproductive neuroendocrinology have identified several non-steroidal compounds capable of reactivating the reproductive axis by targeting central regulatory pathways. Among these, kisspeptin analogs directly stimulate KISS1R-expressing neurons, inducing robust GnRH/LH secretion and reinitiating …
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BM Sürdürülebilir Kalkınma Amaçları
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