Is the Lactate/Albumin Ratio Associated with 28-Day Mortality in Critically Ill Patients That Underwent Open Gastric Cancer Surgery? A Retrospective Single-Center Study
Yazarlar (3)
Yavuz Selim Kahraman
Kastamonu Training And Research Hospital, Türkiye
Kastamonu Training And Research Hospital, Türkiye
Doç. Dr. Veysel Garani SOYLU Kastamonu Üniversitesi, Türkiye
Doç. Dr. Öztürk TAŞKIN Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Journal of Clinical Medicine (Q1) | ||
| Dergi ISSN | 2077-0383 Dergi Bilgileri (2026) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2026 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 28-04-2026 |
| Cilt / Sayı / Sayfa | 15 / 9 / – | DOI | 10.3390/jcm15093345 |
| Makale Linki | https://doi.org/10.3390/jcm15093345 | ||
| UAK Araştırma Alanları |
Yoğun Bakım
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| Özet |
| Objectives The aim of this study is to investigate the relationship between the lactate/albumin ratio (LAR) and 28-day mortality in gastric cancer patients undergoing monitoring in a postoperative intensive care unit due to reasons such as haemodynamic instability, need for vasopressor support, or intraoperative bleeding. Methods This retrospective study included patients followed up at the tertiary surgical intensive care unit of Kastamonu University Faculty of Medicine between January 2020 and October 2025 who were diagnosed with histologically confirmed gastric adenocarcinoma and underwent total open surgery or subtotal gastrectomy + D2 lymphadenectomy. The patients were categorized into two groups: non-survivors within 28 days (n: 45) and survivors within 28 days (n: 139). Results A total of 184 critically ill patients (110 males, 74 females) who underwent gastric adenocarcinoma surgery and were followed up in the surgical intensive care unit were included in this study. The mean age of the patients was 72.2 ± 11.3 years. Of these patients, 139 (75.5%) were survivors, and 45 (24.5%) were non-survivors. Albumin, the C-reactive protein (CRP)/albumin ratio, lactate, and the lactate/albumin ratio were associated with 28-day mortality. Receiver operating characteristic (ROC) analysis showed that the LAR (area under the curve (AUC): 0.839) was superior to the serum albumin (AUC: 0.736) and lactate levels (AUC: 0.796) for predicting 28-day mortality. The optimal cut-off value of the LAR was 0.82, and an LAR of ≥ 0.82 was shown to be a significant and independent prognostic factor for 28-day mortality in patients with stomach cancer in … |
| Anahtar Kelimeler |
| 28-day mortality | gastric cancer | intensive care | lactate/albumin ratio |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Scopus | 1 |
| Google Scholar | 3 |