The Predictive Role of the Triglyceride/High-Density Lipoprotein Ratio and the Triglyceride–Glucose Index, Along with Anthropometric Measurements, in Diagnosing Non-Alcoholic …
Yazarlar (9)
Emrah Çığrı
Funda Çatan İnan
Doç. Dr. Sedat GÜLTEN Türkiye
Mehmet Akif Bildirici
Ayşe Ece Gökkaya
Metin Asıleren
Mustafa Koyun
Bahadır Reis
Merve Esen Kastamonu Üniversitesi
| Makale Türü | Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Children | ||
| Makale Dili | – | Basım Tarihi | 10-2025 |
| Cilt / Sayı / Sayfa | 12 / 11 / 1439–0 | DOI | – |
| Makale Linki | https://www.mdpi.com/2227-9067/12/11/1439 | ||
| UAK Araştırma Alanları |
Tıbbi Biyokimya
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| Özet |
| Highlights Our article is about practical methods that we can use in the early detection of non-alcoholic fatty liver disease, which is common in obese children. What are the main findings? TG/HDL ratio and TyG index show a significant increase in obese children with NAFLD. Cardiovascular risk indices increase in obese children with NAFLD. What is the implication of the main finding? TG/HDL ratio and TyG index are very significant parameters in the early detection of NAFLD. The development of NAFLD in obese children also increases the risk of cardiovascular disease. Abstract Aim: This current research aims to determine the predictive value of the ratio of triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C), index of triglyceride–glucose (TyG), homeostatic model assessment for insulin resistance (HOMA-IR) score, and anthropometric measurements at the onset of non-alcoholic fatty liver disease (NAFLD) in obese kids and juveniles. It also sought to assess how novel cardiovascular risk markers are affected in obese pediatric patients with NAFLD. Materials and Methods: Between November 2024 and May 2025, a total of 199 pediatric patients were prospectively evaluated, including 150 children with obesity and 49 entirely healthy controls. Two categories of obese patients were created based on whether or not they had non-alcoholic fatty liver disease. These groups were compared with each other and with the control group in terms … |
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