Spectroscopic Investigation of the Effects of Syntrichia ruraliformis (Besch.) Mans., Hypnum andoi AJE Sm. and Platyhypnidium riparioides Dixon Ethanol Extracts on HCT116 Cell …
Yazarlar (4)
Hilal Zengin Köksal
Dilsad Özerkan
Prof. Dr. Ergin Murat ALTUNER Kastamonu Üniversitesi, Türkiye
Kerem Canli Kastamonu Üniversitesi
| Makale Türü | Özgün Makale (Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Anatolian Bryology | ||
| Makale Dili | – | Basım Tarihi | 11-2021 |
| Cilt / Sayı / Sayfa | 7 / 2 / 109–118 | DOI | – |
| Makale Linki | http://altuner.me/A59.php | ||
| UAK Araştırma Alanları |
Biyokimya
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| Özet |
| Colon cancer is the third most common type of cancer in the world, with more than a million new diagnoses every year. As can be seen in all age groups, it is not inherited. Considering these data, it is an important need to research new drug combinations for the treatment of cancer. In this study, the effects of extracts obtained from Syntrichia ruraliformis (Besch.) Mans., Hypnum andoi A.J.E.Sm, Platyhypnidium riparioides Dixon bryophyte species with unknown anticancer activity against HCT116 colon cancer cell lines were evaluated. Cytotoxicity test (MTT) experiments were performed at various concentrations by preparing stock solutions with DMSO from extracts of moss species obtained in ethyl alcohol solvent. The doses determined according to the IC50 values of all moss species in the HCT116 series were applied to the mesenchymal stem cells (MSCs) in the same way. In addition, Fourier transform infrared … |
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