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Biochemical and Pathological Effects on The Male Rat Hepatic Tissue After Exposure to 900mhz Electromagnetic Field During Adolescent Period    
Yazarlar (9)
Ayşe İkinci Keleş
Türkiye
Hüseyin Serkan Erol
Türkiye
Tuğçe Sapmaz
Türkiye
Tolga Mercantepe
Türkiye
Gökhan Keleş
Türkiye
Burcu Biterge Süt
Türkiye
Ersan Odacı
Türkiye
Mesut Bünyami Halıcı
Türkiye
Sait Polat
Türkiye
Devamını Göster
Özet
The aim of this study was to employ biochemical analysis and histopathological techniques to investigate the effects of the application of a 900-megahertz electromagnetic field during adolescence on the rat liver. 24 male Sprague Dawley rats aged 21 days were randomly divided into electromagnetic field, sham and control groups. No procedure was performed on the control group rats. Electromagnetic field group rats were exposed to a 900-megahertz electromagnetic field in an electromagnetic field application cage (1 hours/day, every day for 25 days). The sham group rats were placed in the same electromagnetic field cage without exposure to electromagnetic field. At the end of the experiments, the livers were removed. The livers were used for histopathological evaluation (light, electron and immunofluorescence microscopy) and biochemical analyses. Biochemical analyses revealed increased lipid peroxidation and glutathione values while catalase and superoxide dismutase values were decreased in electromagnetic field group. Electron microscopy evaluations identified necrotic hepatocytes with numerous cytoplasmic and mitochondrial vacuoles in electromagnetic field group sections. We also observed an enlarged endoplasmic reticulum and loss of mitochondrial matrix, in addition to the presence of vacuoles. Also, loss of inner and outer mitochondrial membrane integrity was observed. Light microscopy evaluations revealed sinusoidal capillary dilatation and degeneration in hepatocytes with cytoplasmic swelling, vacuolar degeneration and pyknotic nuclei in electromagnetic field group sections. Deterioration in the integrity of the …
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayınlanan tam makale
Dergi Adı Communications Faculty of Sciences University of Ankara Series C Biology
Dergi ISSN 1303-6025
Dergi Tarandığı Indeksler Zoological Records
Makale Dili Türkçe
Basım Tarihi 01-2021
Cilt No 30
Sayı 1
Sayfalar 25 / 46
Makale Linki https://dergipark.org.tr/en/download/article-file/1189560
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