Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900MHz electromagnetic field during early and mid adolescence
Yazarlar (11)
Ayşe İkinci Keleş Niğde Ömer Halisdemir Üniversitesi, Türkiye
Tolga Mercantepe Recep Tayyip Erdoğan Üniversitesi, Türkiye
Deniz Ünal Türkiye
Doç. Dr. Hüseyin Serkan Erol Atatürk Üniversitesi, Türkiye
Doç. Dr. Arzu Şahin Uşak Üniversitesi, Türkiye
Prof. Dr. Ali Aslan Ordu Üniversitesi, Türkiye
Orhan Baş Ordu Üniversitesi, Türkiye
Prof. Dr. Havva Erdem Ordu Üniversitesi, Türkiye
Osman Fikret Sönmez
Dr. Öğr. Üyesi Haydar Kaya Karadeniz Teknik Üniversitesi, Türkiye
Ersan Odacı Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | JOURNAL OF CHEMICAL NEUROANATOMY | ||
| Dergi ISSN | 0891-0618 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 09-2016 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-09-2016 |
| Cilt / Sayı / Sayfa | 75 / 1 / 99–104 | DOI | 10.1016/j.jchemneu.2015.11.006 |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S0891061815000964 | ||
| UAK Araştırma Alanları |
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| Özet |
| The effects of devices emitting electromagnetic field (EMF) on human health have become the subject of intense research among scientists due to the rapid increase in their use. Children and adolescents are particularly attracted to the use of devices emitting EMF, such as mobile phones. The aim of this study was therefore to investigate changes in the spinal cords of male rat pups exposed to the effect of 900 MHz EMF. The study began with 24 Sprague-Dawley male rats aged 3 weeks. Three groups containing equal numbers of rats were established—control group (CG), sham group (SG) and EMF group (EMFG). EMFG rats were placed inside an EMF cage every day between postnatal days (PD) 21 and 46 and exposed to the effect of 900 MHz EMF for 1 h. SG rats were kept in the EMF cage for 1 h without being exposed to the effect of EMF. At the end of the study, the spinal cords in the upper thoracic region of all rats were removed. Tissues were collected for biochemistry, light microscopy (LM) and transmission electron microscopic (TEM) examination. Biochemistry results revealed significantly increased malondialdehyde and glutathione levels in EMFG compared to CG and SG, while SG and EMFG catalase and superoxide dismutase levels were significantly higher than those in CG. In EMFG, LM revealed atrophy in the spinal cord, vacuolization, myelin thickening and irregularities in the perikarya. TEM revealed marked loss of myelin sheath integrity and invagination into the axon and broad vacuoles in axoplasm. The study results show that biochemical alterations and pathological changes may occur in the spinal cords of male rats following exposure to 900 MHz EMF for 1 h a day on PD 21–46. |
| Anahtar Kelimeler |
| Electromagnetic field | Light microscopy | Male rat | Mobile phone | Spinal cord | Transmission electron microscopy |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |