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Pathological effects of prenatal exposure to a 900 MHz electromagnetic field on the 21 day old male rat kidney       
Yazarlar
Ersan Odacı
Türkiye
Deniz Ünal
Türkiye
Tolga Mercantepe
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Zehra Topal Suzan
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Hatice Hancı
Ordu Üniversitesi, Türkiye
Sibel Türedi
Harran Üniversitesi, Türkiye
Doç. Dr. Hüseyin Serkan EROL
Atatürk Üniversitesi, Türkiye
Sevdegül Aydın Mungan
Karadeniz Teknik Üniversitesi, Türkiye
Haydar Kaya
Karadeniz Teknik Üniversitesi, Türkiye
Serdar Çolakoğlu
Düzce Üniversitesi, Türkiye
Özet
We investigated the effects on kidney tissue of 900 megahertz (MHz) EMF applied during the prenatal period. Pregnant rats were exposed to 900 MHz EMF, 1 h/day, on days 13-21 of pregnancy; no procedure was performed on control group pregnant rats or on mothers or newborns after birth. On postnatal day 21, kidney tissues of male rat pups from both groups were examined by light and electron microscopy. Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione levels also were investigated. Light microscopy revealed some degenerative changes in the tubule epithelium, small cystic formations in the primitive tubules and large cysts in the cortico-medullary or medullary regions in the experimental group. Electron microscopy revealed a loss of peritubular capillaries and atypical parietal layer epithelial cells in the experimental group. Biochemical analysis showed significantly increased MDA levels in the experimental group and decreased SOD and CAT levels. EMF applied during the prenatal period can caused pathological changes in kidney tissue in 21-day-old male rats owing to oxidative stress and decreased antioxidant enzyme levels.
Anahtar Kelimeler
Antioxidant enzymes | Cell phone | Electromagnetic field | Kidney | Male rat
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı BIOTECHNIC HISTOCHEMISTRY
Dergi ISSN 1052-0295
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 02-2015
Cilt No 90
Sayı 2
Sayfalar 93 / 101
Doi Numarası 10.3109/10520295.2014.947322
Makale Linki http://informahealthcare.com/doi/abs/10.3109/10520295.2014.947322