The Relationship Between Tear Osmolarity Ocular Surface Disease Index and Other Tear Function Tests
Yazarlar (4)
Arzu Taşkıran Çömez
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Dr. Öğr. Üyesi Barış KÖMÜR Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Elif Şanal
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Hasan Ali Tufan
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
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Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Turkiye Klinikleri Journal of Medical Sciences | ||
| Dergi ISSN | 1300-0292 Dergi Bilgileri (2013) | ||
| Dergi Tarandığı Indeksler | EMBASE, Scopus, EBSCO/CINAHL, Chemical Abstracts Service (CAS), ProQuest, Turkiye Citiation Index, Turkiye Klinikleri Medical Database | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2013 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2013 |
| Cilt / Sayı / Sayfa | 33 / 2 / 455–463 | DOI | 10.5336/medsci.2012-30139 |
| Makale Linki | http://www.tipbilimleri.turkiyeklinikleri.com/abstract_64452.html | ||
| UAK Araştırma Alanları |
Göz Hastalıkları
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| Özet |
| Objective To evaluate the relationship between tear osmolarity, Ocular Surface Disease Index (OSDI© Allergan Inc., Irvine, Calif), Schirmer test and tear break-up time (TBUT). Material and Methods After performing Ocular Surface Disease Index (OSDI©) survey, tear osmolarity testing with TearLab osmolarity system, Schirmer test without anesthesia and TBUT measurement were performed in 40 patients with dry eye syndrome diagnosis and 39 healthy subjects. Student t-test and Spearman's rho correlation analysis are used for statistical evaluation. Results The mean tear osmolarity was 307±19.2 mOsm/l in group A, while it was 292.9±13.9 mOsm/l in group B. Schirmer test results were in normal ranges in both groups (13.4±7.5 mm in group A, and 17.4±8.5 mm in group B). TBUT was lower in group A, and the difference between two groups was statistically significant. OSDI© scoring was 43.9±20.4 in group A, while it was 8.56±5.2 in group B and the difference was statistically significant. The sensitivity and spesificity of tear osmolarity for threshold value 305 mOsm/l were found to be 76.9% and 80%, for TBUT for 10 seconds were 94.7% and 71.8%; for OSDI© score> 15 were 79.5% and 70% and for Schirmer's test for 10 mm were 35.9% and 80%. Conclusion Of all tests, TBUT, tear osmolarity and OSDI© are found to be successful in discriminating dry eye patients from healthy participants. The specificity and the sensitivity of the commonly used Schirmer test are found to be low.© 2013 by Türkiye Klinikleri. |
| Anahtar Kelimeler |
| Diagnostic tests | Dry eye syndromes | Osmolar concentration | Routine | Sensitivity and specificity | Tears |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 2 |
| Google Scholar | 4 |