| Yazarlar |
Prof. Dr. Zafer ERGÜL
Kastamonu Üniversitesi, Türkiye |
Duray Şeker
Sağlık Bilimleri Üniversitesi, Türkiye |
|
Celil Uğurlu
|
|
Melih Akıncı
Sağlık Bilimleri Üniversitesi, Türkiye |
|
Hakan Kulaçoğlu
|
|
Engin Olçücüoğlu
|
| Özet |
| The surgical infection rate is not low in some series of elective pilonidal sinus surgery despite single dose antibiotic prophylaxis. This study was designed to compare wound infection rate after a single dose and a 5-day intravenous course of cefazolin plus metranidazole administration in patients who were operated employing Karydakis flap for pilonidal sinus. Material and Methods: A total of 50 patients were involved in this prospective randomised clinical study. Karydakis flap procedure was used and a vacuum drain was left in situ in all cases. The patients were divided into two groups: Group 1 had either a single dose of 500 mg metranidazole plus 500 mg cefazolin sodium IV for prophylaxis and Group 2 were subjected to same preoperative drugs IV followed by their oral administration for five days (Sefazol 500 mg tablet plus Flagyl 500 mg tablet, twice a day). The surgical site infection rate, total drainage volume and drain removal time were recorded. Results: The study was truncated because of occurence of an unacceptable infection rate, thus, 30 patients were able to continue on the study. Five surgical site infections were observed in 14 patients in Group 1 (35.71%) whereas only one infection was recorded in 16 patients in Group 2 (6.25%). Although the target patient number was not reached, the statistical difference was already achieved (p= 0.04). The mean total drainage volume was greater in Group 1 than in Group 2 (91.42 v.s. 72.12 ml; p= 0.073). However, the mean drain removal times were similar. Conclusion: The wound infection rate is high in elective pilonidal sinus surgery. Single dose prophylactic antibiotic combination may not be sufficient to avoid wound infection in pilonidal sinus surgery in which Karydakis flap technique is used. © 2011 by Türkiye Klinikleri. |
| Anahtar Kelimeler |
| Antibiotic prophylaxis | Cefazolin | Pilonidal sinus | Surgical wound infection |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Turkiye Klinikleri J Med Sci, 31 (1), 186-190, (2011). |
| Dergi ISSN | 1300-0292 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2011 |
| Cilt No | 31 |
| Sayı | 1 |
| Sayfalar | 186 / 190 |
| Doi Numarası | 10.5336/medsci.2009-14965 |
| Atıf Sayıları | |
| SCOPUS | 6 |
| Google Scholar | 11 |
