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Topical antibiotic prophylaxis in lichtenstein hernia repair and comparison of three methods: A prospective randomized clinical trial   
Yazarlar
Duray Şeker
Sağlık Bilimleri Üniversitesi, Türkiye
Gaye Necipoğlu
Bahattin Bayer
Prof. Dr. Zafer ERGÜL Prof. Dr. Zafer ERGÜL
Kastamonu Üniversitesi, Türkiye
Hakan Kulaçoğlu
Özet
INTRODUCTION: Lichtenstein hernia repair is a clean surgical intervention and one of the most frequently applied operation worldwide. Despite guidelines, benefit of antibiotic prophylaxis in hernia surgery has been considered questionable and prophylaxis usage is not infrequent. Here, in this clinical randomized trial, we aimed to compare three different prophylaxis regimens to find out which one is more effective. METHODS: In this prospective study, patients were divided into three groups. First group (G1) received cefazoline, second group (G2) received topical gentamicin, and third group (G3) received combination of cefazoline and topical gentamicin. On 1st, 7th, and 30thpostoperative days, surgical sites were examined for the signs of infection according to the definitions of Centers for Disease Control. Furthermore, effectiveness of infection prevention in patients with comorbid diseases was also analyzed. RESULTS: Totally 276 patients were analyzed. In G1 three, in G2 two, and in G3 0 infections were recorded. Total, infection rate was 1.8%. There was no any difference in infection rates between three groups (P = 0.285). Comorbidities did not rise infection rates under prophylaxis coverage (P > 0.05). CONCLUSION: All three methods are equally effective in surgical site infection, but combination method seems better with '0' ratio. Prophlaxy coverage also prevents surgical site infection even in the presence of risk (comorbidities).
Anahtar Kelimeler
Anti-bacterial agents | Hernia | Infection | Prevention and control | Wounds
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayımlanan tam makale
Dergi Adı international Journal of Abdominal Wall and Hernia Surgery
Dergi ISSN 2589-8736
Dergi Tarandığı Indeksler DOAJ
Makale Dili İngilizce
Basım Tarihi 03-2021
Cilt No 4
Sayı 2
Sayfalar -58 / -65
Doi Numarası 10.4103/ijawhs.ijawhs_6_21
Makale Linki www.herniasurgeryjournal.org