| Yazarlar |
Ölçücüoğlu Engin
|
|
Hakan Kulaçoğlu
|
|
Cemal Ensari
|
|
Alper Yavuz
|
Prof. Dr. Zafer ERGÜL
Kastamonu Üniversitesi, Türkiye |
| Özet |
| Background: Chronic pain after mesh repair for inguinal hernia may be related to the trauma to the regional nerves by direct compression with sutures, staples, or tacks during mesh fixation. Fibrin sealant (FS) has been recommended to eliminate this risk. In this experimental study, the effects of FS on the ilioinguinal nerve when a mesh was applied was searched. Materials and Methods: Fifteen New Zealand rabbits were used in three groups. In Group 1, a 2×1 cm, standard monofilament, pure polypropylene mesh was laid over ilioinguinal nerve. In Group 2, 0.5 ml FS was applied on the nerve without using an onlay mesh. In Group 3, a 2×1 cm mesh was laid onlay and secured with 0.5 ml FS with no fixating suture. Three months after surgery bilateral nerve samples were taken from the contiguous nerve segment for microscopic study. Results: Group 1 showed prominent findings with regard to all parameters. There were significant differences between Group 1 and Group 2 in respect of fibrosis, lymphocyte, and edema scores, and foreignbody reaction. The values of Group 3, where the mesh was secured by the application of FS with no suture, were roughly placed in between Group 1 and Group 2. Prominent fibrosis and increased collagen proliferation in peripheral area of mesh was seen in Group 1 subjects, whereas a mild fibroblastic activity among mesh fibers in Group 3 subjects. Conclusions: FS has no negative effect on ilioinguinal nerve. FS application may protect the nerve from the harmful effects of polypropylene mesh in inguinal hernia repair. © 2011 Informa Healthcare USA, Inc. |
| Anahtar Kelimeler |
| Experimental | Fibrin sealant | Ilioinguinal nerve | Inguinal hernia | Mesh | Postoperative pain |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | Diğer hakemli uluslarası dergilerde yayımlanan tam makale |
| Dergi Adı | J Invest Surg. |
| Dergi ISSN | 0894-1939 |
| Dergi Tarandığı Indeksler | IM: Index Medicus |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2011 |
| Cilt No | 24 |
| Sayı | 5 |
| Sayfalar | 267 / 272 |
