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Effects of dietary marine sulphated polysaccharides (Algimun®) on growth performance, immune responses and disease resistance of juvenile gilthead seabream (Sparus aurata) to Photobacterium damselae subsp. piscicida       
Yazarlar
Derya Güroy
Yalova Üniversitesi, Türkiye
Betül Güroy
Yalova Üniversitesi, Türkiye
Doç. Dr. Soner BİLEN
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Ertuğrul TERZİ
Kastamonu Üniversitesi, Türkiye
Arş. Gör. Dr. Osman Nezih KENANOĞLU
Kastamonu Üniversitesi, Türkiye
MarÍa GarcÍa-SuÁrez
DaniÈle Marzin
Serhan Mantoğlu
Yalova Üniversitesi, Türkiye
Onur Karadal
İzmir Katip Çelebi Üniversitesi, Türkiye
İzzet Şahin
Yalova Üniversitesi, Türkiye
Halit Kuşku
Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Özet
The present study evaluated the effects of a dietary mix of marine sulphated polysaccharides, named Algimun® (AL), supplementation to gilthead seabream (Sparus aurata) juveniles in terms of growth performance, immune responses, and resistance against Photobacterium damselae subsp. piscicida. A total of 240 fish (initial mean weight of 6.00 ± 0.03 g) was randomly separated into 12 tanks (400 L, 20 fish per tank) distributed in four replicates. Fish were fed three experimental diets: a basal diet (Control), and a basal diet with two inclusion rates of Algimun® as 3 g/kg (AL0.3) and 5 g/kg (AL0.5) for 30 days before bacterial infection with P. damselae subsp. piscicida. After a 30-day feeding-period, growth performance was significantly improved in AL0.3 and AL0.5 groups compared to the control group (P < 0.05). AL0.3 and AL0.5 groups showed significantly higher lysozyme activity and myeloperoxidase activity when compared to the control group (P < 0.05). The gene expression of immune mediators (IL-1β, IL-6, IL-10, IL-18, TNF-α and COX-2) was significantly upregulated in the intestine, spleen and head kidney in AL0.3 and AL0.5 groups when compared to the control group (P < 0.05). Eight days post-challenge, the survival rate against P. damselae subsp. piscicida was numerically higher in fish within AL0.3 and AL0.5 groups compared to control (+20%). The study findings suggest that marine sulphated polysaccharides (Algimun®) could be used as an immunomodulator in gilthead seabream to support animal's health and boost resistance in case of disease outbreak.
Anahtar Kelimeler
Immunomodulation | Marine fish | Marine sulphate polysaccharide | Nutrition | Seaweed
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı FISH & SHELLFISH IMMUNOLOGY
Dergi ISSN 1050-4648
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q1
Makale Dili İngilizce
Basım Tarihi 08-2022
Cilt No 127
Sayı 1
Sayfalar 1139 / 1147
Doi Numarası 10.1016/j.fsi.2022.07.054
Makale Linki https://doi.org/10.1016/j.fsi.2022.07.054