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Effects of dietary Astragalus caudiculosus (Boiss & Huet, 1856) supplementation on growth, hematology, antioxidant enzyme activities, and immune responses in rainbow trout (Oncorhynchus mykiss Walbaum, 1792)        
Yazarlar
Doç. Dr. Adem Yavuz SÖNMEZ
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Soner BİLEN
Kastamonu Üniversitesi, Türkiye
Arş. Gör. Dr. Yiğit TAŞTAN
Kastamonu Üniversitesi, Türkiye
Arş. Gör. Dr. Osman Nezih KENANOĞLU
Kastamonu Üniversitesi, Türkiye
Doç. Dr. Ertuğrul TERZİ
Kastamonu Üniversitesi, Türkiye
Özet
The potential dietary utilization of Astragalus caudiculosus (AC) in rainbow trout (Oncorhynchus mykiss) was investigated. Four different fish groups (control, AC1, AC2.5, and AC5) were assigned and received the AC-containing diet for 90 days at the rates of 0, 1, 2.5, and 5%, respectively. Results indicated that the growth performance of the AC supplemented fish improved significantly (P < 0.05). Among non-specific immune parameters examined, while lysozyme activity of the AC supplemented fish increased (P < 0.05), oxidative radical production decreased in AC1 and AC2.5 fish groups (P < 0.05) but did not differ in the AC5 group (P > 0.05) compared to the control. Moreover, myeloperoxidase activity was not affected by the AC supplementation (P > 0.05). All pro-inflammatory and anti-inflammatory cytokine gene expressions, except IL-1β, were up-regulated, especially in the fish groups fed with 2.5 and 5% AC supplemented feed (P < 0.05). AC administration caused an elevation in GPx and G6PDH activities, and a decrease in SOD, CAT, and lipid peroxidation (P < 0.05). Overall, AC extract was found to improve the growth, antioxidant status, and immune response of the fish.
Anahtar Kelimeler
Astragalus | Cytokine gene expression | Feed additive | Growth performance | Immune response | Rainbow trout
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı FISH & SHELLFISH IMMUNOLOGY
Dergi ISSN 1050-4648
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q1
Makale Dili Türkçe
Basım Tarihi 03-2022
Cilt No 122
Sayı 1
Sayfalar 366 / 375
Doi Numarası 10.1016/j.fsi.2022.02.031
Makale Linki https://www.sciencedirect.com/science/article/pii/S1050464822000936