Mucus from different fish species alleviates carrageenan-induced inflammatory paw edema in rats
Yazarlar (7)
Mustafa Hitit
Kastamonu Üniversitesi, Türkiye
Kastamonu Üniversitesi, Türkiye
Prof. Dr. Orhan Corum Kastamonu Üniversitesi, Türkiye
Prof. Dr. Mehmet Ozbek Burdur Mehmet Akif Ersoy Üniversitesi, Türkiye
Prof. Dr. Kamil Uney Selçuk Üniversitesi, Türkiye
Doç. Dr. Ertuğrul TERZİ Kastamonu Üniversitesi, Türkiye
Doç. Dr. Gokhan Arslan Atatürk Üniversitesi, Türkiye
Prof. Dr. A. Y. Sonmez Kastamonu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Asian Pacific Journal of Tropical Biomedicine (Q2) | ||
| Dergi ISSN | 2221-1691 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2020 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2020 |
| Cilt / Sayı / Sayfa | 10 / 10 / 452–459 | DOI | 10.4103/2221-1691.290870 |
| Makale Linki | http://www.apjtb.org/text.asp?2020/10/10/452/290870 | ||
| UAK Araştırma Alanları |
Su Kalitesi ve Su Kirliliği
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| Özet |
| Objective:To determine the anti-inflammatory effects of mucus obtained from different fish species on the carrageenan-induced acute paw edema in rats.Methods:Forty-two rats were randomly divided into seven groups. Acute paw edema was induced by 0.1 mL of 1% carrageenan, and a single dose of diclofenac and lyophilized mucus (25 mg/kg) of rainbow trout, brook trout, European sea bass, and gilthead sea bream were administered to rats through gastric gavage 1 h before carrageenan treatment. Rat paws were measured before and 1-4 h after carrageenan treatment. The mRNA expressions of cytokines (TNF-α, IL-1β, IL-6, IL-10, and TGF-β), antioxidant markers (catalase and superoxide dismutase), and COX-2 were investigated using quantitative polymerase chain reaction. The histopathological changes were evaluated by hematoxylin and eosin staining.Results:The inhibition percentage of carrageenan … |
| Anahtar Kelimeler |
| Carrageenan | Fish mucus | Inflammation | Rat paw edema |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 7 |
| Google Scholar | 9 |