Assessment of acute toxicity and histopathology of the fungicide captan in rainbow trout
       
Yazarlar (4)
Halis Boran Karadeniz Technical University, Türkiye
Erol Çapkın Karadeniz Technical University, Türkiye
İlhan Altınok Karadeniz Technical University, Türkiye
Doç. Dr. Ertuğrul TERZİ Karadeniz Technical University, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Experimental and Toxicologic Pathology
Dergi ISSN 0940-2993 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 03-2012
Cilt / Sayı / Sayfa 64 / 3 / 175–179 DOI 10.1016/j.etp.2010.08.003
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S0940299310001351
Özet
Acute toxicity of the fungicide, captan, to juvenile rainbow trout was evaluated under static-renewal test condition. Actual concentrations of captan ranged from 0.05 to 1.00mg/L. The concentrations of captan that killed 50% of the rainbow trout (3.11±0.8g) within 24 (24h; LC 50), 48, 72 and 96h were 0.57±0.09, 0.49±0.10, 0.44±0.11 and 0.38±0.13mg/L (95% confidence limits), respectively. None of the unexposed control fish died and the first fish died 6h after exposure to captan (≥0.65mg/L). Hypertrophy, separation of epithelium from lamellae, lamellar fusion, and epithelial cell necrosis were observed on captan exposed fish. Gills also had scattered areas of focal lamellar hyperplasia. Fish exposed to fungicide had inflammation and necrosis in liver, trunk kidney and spleen. In order, the most affected organs were gill, trunk kidney and liver. © 2010 Elsevier GmbH.
Anahtar Kelimeler
Acute toxicity test | Captan | Histopathology | Rainbow trout