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How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?.   
Yazarlar
Prof. Dr. Zafer ERGÜL Prof. Dr. Zafer ERGÜL
Kastamonu Üniversitesi, Türkiye
Mehmet Ali Karahan
Duray Şeker
Sağlık Bilimleri Üniversitesi, Türkiye
Hakan Kulaçğlu
Demet Yılmazer
Özet
Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing. © 2009 Versita Warsaw and Springer-Verlag Berlin Heidelberg.
Anahtar Kelimeler
Hernia repair | Malnutrition | Mesh | Tensile strength | Wound healing
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayımlanan tam makale
Dergi Adı Cent.Eur.J.Med
Dergi ISSN 1895-1058
Dergi Tarandığı Indeksler IM: Index Medicus
Makale Dili İngilizce
Basım Tarihi 07-2009
Cilt No 4
Sayı 3
Sayfalar 331 / 336
Doi Numarası 10.2478/s11536-009-0029-2