How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?.
Yazarlar (5)
Prof. Dr. Zafer ERGÜL Kastamonu Üniversitesi, Türkiye
Mehmet Ali Karahan
T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi, Türkiye
Duray Şeker
Sağlık Bilimleri Üniversitesi, Türkiye
Hakan Kulaçğlu
T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi, Türkiye
Demet Yılmazer
T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
Dergi Adı Central European Journal of Medicine
Dergi ISSN 1895-1058
Dergi Tarandığı Indeksler IM: Index Medicus
Makale Dili İngilizce Basım Tarihi 07-2009
Cilt / Sayı / Sayfa 4 / 3 / 331–336 DOI 10.2478/s11536-009-0029-2
Makale Linki https://www.degruyter.com/document/doi/10.2478/s11536-009-0029-2/pdf
UAK Araştırma Alanları
Genel Cerrahi
Özet
Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing. © 2009 Versita Warsaw and Springer-Verlag Berlin Heidelberg.
Anahtar Kelimeler
Hernia repair | Malnutrition | Mesh | Tensile strength | Wound healing