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| Dergi Adı | Journal of endocrinological investigation (Q3) | ||
| Dergi ISSN | 0391-4097 | ||
| Makale Dili | – | Basım Tarihi | 01-2015 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 29-11-2014 |
| Cilt / Sayı / Sayfa | 38 / 4 / 463–469 | DOI | 10.1007/s40618-014-0216-0 |
| Makale Linki | https://link.springer.com/article/10.1007/s40618-014-0216-0 | ||
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| Özet |
| PurposeThe association of obstructive sleep apnea syndrome (OSAS) and metabolic syndrome (MS) has been demonstrated in studies and in recent years; the effect of OSAS on insulin resistance independent of the level of obesity is being investigated. Nesfatin-1 is a newly defined 82 amino acid protein with a precursor molecule of NUCB2 (nucleobindin 2). Nesfatin-1 is not only essential in regulation of food ingestion but also important in regulation of some brain functions, autonomic regulation, stress, mental state, and paradoxical sleep. We aimed to evaluate the relationship between OSAS and MS and the MS dependent or independent effect of Nesfatin-1 on this relationship.MethodsPatients admitted with clinical signs of OSAS are included. Patients are divided into three groups based on Apnea-Hypopnea Index (AHI) on Polysomnography (PSG) as mild, moderate, and severe OSAS. A total of 59 patients … |
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| Google Scholar | 35 |