Osteoprotegerin is associated with subclinical left ventricular systolic dysfunction in diabetic hypertensive patients: a speckle tracking study
Yazarlar (9)
MD Ezgi Kalaycıoğlu
MD Tayyar Gökdeniz
MD Ahmet Çağrı Aykan
MD Engin Hatem
MD Mustafa Ozan Gürsoy
MD Asım Ören
MD Hüseyin Yaman
Dr. Öğr. Üyesi Mertcan KARADENİZ Kastamonu Üniversitesi, Türkiye
MD Şükrü Çelik
Kastamonu Üniversitesi
Kastamonu Üniversitesi
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Canadian Journal of Cardiology (Q2) | ||
| Makale Dili | – | Basım Tarihi | 12-2014 |
| Cilt / Sayı / Sayfa | 30 / 12 / 1529–1534 | DOI | – |
| Makale Linki | https://www.sciencedirect.com/science/article/pii/S0828282X14012860 | ||
| UAK Araştırma Alanları |
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| Özet |
| BackgroundRecently, the role of osteoprotegerin (OPG) in the pathogenesis of heart failure through different mechanisms has received much attention. Subclinical changes in left ventricular (LV) function can be identified using quantification of myocardial strain, and global longitudinal strain (GLS) is a superior predictor of outcomes than ejection fraction. We hypothesized that increased OPG levels could predict subclinical LV systolic dysfunction in treated diabetic hypertensive patients with preserved LV ejection fraction.MethodsThe study was composed of 86 diabetic hypertensive and 30 nondiabetic hypertensive patients. All patients underwent echocardiography and venous blood samples were taken for determination of OPG. The relation between OPG levels and LV GLS was investigated using 2-dimensional speckle tracking echocardiography.ResultsDiabetic hypertensive patients had higher diastolic peak … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 14 |