Yazarlar |
Sermin Algül
Türkiye |
Feray Ferda Şenol
|
Seda Uğraş
Türkiye |
Fatih Esmer
Türkiye |
Mehmet Kara
Türkiye |
Pınar Ekici
Türkiye |
Prof. Dr. Oğuz ÖZÇELİK
Türkiye |
Özet |
This study aimed to determine whether the changes in the metabolism of Brucella patients affect the irisin hormone. Also, it is aimed to investigate the relationships between other laboratory findings used in the diagnosis of brucellosis patients and the irisin hormone.160 persons (80 brucellosis, 80 controls) were included in this study. Blood was drawn from the people participating in the study following their overnight fast. Irisin level was measured by ELISA method, CRP and sedimentation levels were measured using autoanalysers and commercial kits.It was determined that the irisin level of Brucella patients was statistically significantly higher than the control group (p <0.05). It was determined that there is a negative correlation between irisin level and CRP and sedimentation level in Brucella patients.In Brucella patients, the higher irisin level than the control group showed a negative correlation with CRP and sedimentation levels, which are infection diagnosis criteria; It suggests that the level of irisin can be considered as a supportive diagnostic marker in these patients. Further studies are needed to evaluate irisin hormone as a supportive diagnostic criterion. |
Anahtar Kelimeler |
Brucella | C-reactive protein | Infection | Irisin | Sedimentation |
Makale Türü | Özgün Makale |
Makale Alt Türü | Uluslararası alan indekslerindeki dergilerde yayımlanan tam makale |
Dergi Adı | Eastern Journal of Medicine |
Dergi ISSN | 1309-3886 |
Dergi Tarandığı Indeksler | index copernicus |
Makale Dili | İngilizce |
Basım Tarihi | 01-2021 |
Cilt No | 26 |
Sayı | 1 |
Sayfalar | 135 / 138 |
Doi Numarası | 10.5505/ejm.2021.70431 |
Makale Linki | https://jag.journalagent.com/ejm/pdfs/EJM_26_1_129_132.pdf |