| Yazarlar (2) |
Sermin Algül
Yüzüncü Yıl Üniversitesi, Türkiye |
Prof. Dr. Oğuz ÖZÇELİK
Fırat Üniversitesi, Türkiye |
| Özet |
| Obesity is associated with increased risk of many diseases, including diabetes, heart attack, hypertension, cancer and even in early death. Identification of the association between weight gain and hypothalamic functions with respect to hormonal effects will provide a better understanding of obesity. Nesfatin-1, derived from NEFA/nucleobindin2 (NUCB2), is a recently introduced hormone that suppresses food intake via melanocortin system in hypothalamus. Nesfatin-1 administration, through intracerebroventricular, subcutaneous or intraperitoneal injections or even by nasal sprey, inhibited appetite from 3 to 14 hours. In addition, it reduces weight gain, suggesting a role as a new anorexigenic factor and modulator of energy balance. Due to these effects on energy metabolism homeostasis, nesfatin-1 could play an important role in protection against the development of obesity. In recent years, there is a great … |
| Anahtar Kelimeler |
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | F.Ü.Sağ.Bil.Tıp Derg. |
| Dergi Tarandığı Indeksler | TR DİZİN |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2012 |
| Cilt No | 26 |
| Sayı | 3 |
| Sayfalar | 143 / 148 |
